Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5447049 | 0.87 | PDK1 (0.48) | TSHRTRPM8PDK1TSPO | |
| SCHEMBL5881190 | 0.81 | TSHR (0.50) | TSHRTRPM8ALDH1A1GLAHTT | |
| SCHEMBL1927016 | 0.79 | ALDH1A1 (0.69) | TSHRTRPM8NPC1RAB9AALDH1A1 | |
| SCHEMBL1925149 | 0.79 | TDP1 (0.53) | TSHRTRPM8NPC1RAB9AALDH1A1 | |
| SCHEMBL5881182 | 0.78 | TP53 (0.42) | TSHRTRPM8ALDH1A1GLA | |
| SCHEMBL22118149 | 0.78 | TSHR (0.47) | TSHRALDH1A1 | |
| SCHEMBL1259310 | 0.77 | PDK1 (0.58) | TSHRTRPM8NPC1RAB9AALDH1A1 | |
| SCHEMBL7162154 | 0.77 | TSHR (0.41) | TSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3606825 | 0.76 | ACHE (0.47) | TSHRTRPM8NPC1RAB9AALDH1A1 | |
| SCHEMBL11509877 | 0.76 | TSHR (0.46) | TSHRTRPM8NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300407-B2 | CARBAMATES DERIVED FROM ARYLALKYLAMINES | S A L V A T LAB SA (ES) | 2011-06-08 | — | — | EP | claimed |