Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | ILK | Q13418 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30863871 | 1.00 | RAB9A (1.00) | RAB9ANPC1KDM4EILKMEN1 | |
| SCHEMBL12232096 | 0.91 | RAB9A (0.82) | RAB9ANPC1KDM4EILKMEN1 | |
| SCHEMBL12232074 | 0.91 | RAB9A (0.82) | RAB9ANPC1KDM4EILKMEN1 | |
| SCHEMBL12232072 | 0.91 | RAB9A (0.82) | RAB9ANPC1KDM4EILKMEN1 | |
| SCHEMBL24331801 | 0.88 | RAB9A (0.78) | RAB9ANPC1KDM4EILKMEN1 | |
| SCHEMBL12232073 | 0.88 | RAB9A (0.78) | RAB9ANPC1KDM4EILKMEN1 | |
| SCHEMBL24332173 | 0.88 | RAB9A (0.78) | RAB9ANPC1KDM4EILKMEN1 | |
| SCHEMBL20519963 | 0.86 | RAB9A (0.76) | RAB9ANPC1KDM4EILKALDH1A1 | |
| SCHEMBL12232103 | 0.85 | RAB9A (0.74) | RAB9ANPC1KDM4EILKMEN1 | |
| SCHEMBL2482351 | 0.84 | RAB9A (0.72) | RAB9ANPC1KDM4EILKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136718-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230136718-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20200261605-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC | 2020-08-20 | — | — | US | disclosed |
| CN-103450111-B | Green synthesis method of benzothiazole heterocyclic compound | UNIV WENZHOU | 2015-07-08 | — | — | CN | disclosed |
| CN-103304507-B | Green method for preparing heterocyclic compounds from nitriles | UNIV WENZHOU | 2015-02-25 | — | — | CN | disclosed |
| CN-103450111-A | Green synthesis method of benzothiazole heterocyclic compound | UNIV WENZHOU | 2013-12-18 | — | — | CN | disclosed |
| CN-103304507-A | Green method for preparing heterocyclic compounds from nitriles | UNIV WENZHOU | 2013-09-18 | — | — | CN | disclosed |
| US-8481544-B2 | Antibacterial compositions | BIOTA EUROPE LIMITED (GB) | 2013-07-09 | — | — | US | disclosed |
| US-8389516-B2 | Antibacterial compositions | BIOTA EUROPE LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-20120004221-A1 | Antibacterial Compositions | BIOTA EUROPE LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
| US-20110263590-A1 | Antibacterial Compositions | BIOTA EUROPE LIMITED (GB) | 2011-10-27 | — | — | US | disclosed |
| US-7977340-B2 | Antibacterial compositions | PROLYSIS LTD. (GB) | 2011-07-12 | — | — | US | disclosed |
| US-20090197877-A1 | Antibacterial Compositions | PROLYSIS LTD. (GB) | 2009-08-06 | — | — | US | disclosed |
| US-3985885-A | ANTHELMINTIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004221-A1 | Antibacterial Compositions | CYCS, COX6C, RPS6 | RAB9A 3590/4885NPC1 2581/4885KDM4E 3843/4885 |
| US-20090197877-A1 | Antibacterial Compositions | CYCS, COX6C, INTS6 | RAB9A 3588/4885NPC1 3471/4885KDM4E 4304/4885 |
| US-20230136718-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | APBA1, LYPLAL1, APOL1 | RAB9A 1846/4885NPC1 645/4885KDM4E 2843/4885 |
| US-20200261605-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | APBA1, LYPLAL1, APOL1 | RAB9A 1846/4885NPC1 645/4885KDM4E 2843/4885 |
| US-20110263590-A1 | Antibacterial Compositions | CYCS, COX6C, RPS6 | RAB9A 3558/4885NPC1 2378/4885KDM4E 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.