Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118946 | 0.81 | PARP1 (0.41) | RNASEH1PARP1PDE5APDE9APDE1A | |
| SCHEMBL22118862 | 0.79 | PARP1 (0.40) | RNASEH1PARP1PDE5APDE9APDE1A | |
| SCHEMBL22118895 | 0.79 | PARP1 (0.40) | RNASEH1PARP1PDE5APDE9APDE1A | |
| SCHEMBL22119321 | 0.76 | PNP (0.40) | RNASEH1PARP1 | |
| SCHEMBL22118806 | 0.67 | PDE5A (0.36) | RNASEH1PDE5APDE9APDE1APDE1B | |
| SCHEMBL22118843 | 0.67 | ALDH1A1 (0.36) | PARP1 | |
| SCHEMBL22118847 | 0.66 | PDE5A (0.35) | RNASEH1PDE5APDE9APDE1APDE1B | |
| SCHEMBL22118800 | 0.66 | CLPP (0.46) | — | |
| SCHEMBL22118979 | 0.66 | CLPP (0.46) | — | |
| SCHEMBL22119356 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897645-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | Acurx Pharmaceuticals, LLC (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132174-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | ACURX PHARMACEUTICALS, LLC (US) | 2020-06-25 | — | — | WO | disclosed |