⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920610 | 0.81 | — | — | |
| SCHEMBL1755602 | 0.81 | — | — | |
| SCHEMBL16992913 | 0.81 | — | — | |
| SCHEMBL28633047 | 0.81 | — | — | |
| SCHEMBL29879751 | 0.81 | — | — | |
| SCHEMBL2036018 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL8539457 | 0.76 | ALDH1A1 (0.46) | — | |
| SCHEMBL24739800 | 0.75 | HTR6 (0.32) | — | |
| SCHEMBL17449306 | 0.75 | HTT (0.34) | — | |
| SCHEMBL5865115 | 0.75 | NOS3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403562-A | 2',6' -di-2- (1-hydrogen imidazolyl) -4-halogenated pyridine compound and preparation method and application thereof | 深圳大学 | 2022-11-29 | — | — | CN | claimed |
| CN-111317721-B | Nano drug-loaded drug release system, application and preparation method thereof, and preparation method of 2, 6-diphenylpyridine derivative | 深圳金普迈生物科技有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-111317721-A | Nano drug-loaded drug release system, application and preparation method thereof, and preparation method of 2, 6-diphenylpyridine derivative | 深圳金普迈生物科技有限公司 | 2020-06-23 | — | — | CN | claimed |
| EP-4743456-A1 | COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2026-05-20 | — | — | EP | disclosed |
| EP-4658647-A1 | TRICYCLIC AZEPINONE DERIVATIVES AS SYSTEM XC INHIBITORS | UCB Biopharma SRL (BE) | 2025-12-10 | — | — | EP | disclosed |
| EP-4585265-A2 | HETEROARYL INHIBITORS OF PLASMA KALLIKREIN | Takeda Pharmaceutical Company Limited (JP) | 2025-07-16 | — | — | EP | disclosed |
| WO-2025137293-A2 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Roche Sequencing Solutions, Inc. (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-119823106-A | Enhanced nucleic acid polymerization by aromatic compounds | 豪夫迈·罗氏有限公司 | 2025-04-15 | — | — | CN | disclosed |
| US-20250075265-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | ROCHE SEQUENCING SOLUTIONS INC (US) | 2025-03-06 | — | — | US | disclosed |
| WO-2025016314-A1 | COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2025-01-23 | — | — | WO | disclosed |
| EP-4490159-A1 | TRICYCLIC HETEROCYCLE COMPOUNDS AS IAP ANTAGONISTS | Ascentage Pharma (Suzhou) Co., Ltd. (CN) | 2025-01-15 | — | — | EP | disclosed |
| US-6030976-A | SELECTIVE AFFINITY TO 5HT-6 RECEPTORS; CENTRAL NERVOUS SYSTEM DISORDERS; ALZHEIMER'S DISEASE, PSYCHOSES, SCHIZOPHRENIA, MANIC DEPRESSIONS, MEMORY DISORDERS, PARKINSON'S DISEASE, AMYOTROPHIC LATERAL SCLEROSIS AND HUNTINGTON'S DISEASE | HOFFMAN-LA ROCHE INC. (US) | 2000-02-29 | — | — | US | disclosed |
| US-5998665-A | THERAPY FOR NERVOUS SYSTEM DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-12-07 | — | — | US | disclosed |
| US-5939451-A | INDOL-4-YL-BENZENESULFONAMIDES AS ACTIVE MATERIAL TREATING MALARIA, BACTERIAL INFECTION, NEUROLOGICAL DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-08-17 | — | — | US | disclosed |
| US-5932599-A | 4-AMINO-N-(PYRIDINYL-4-YL)-BENZENESULFONAMIDES AS ACTIVE MATERIAL TREATING MALARIA, BACTERIAL INFECTION, NEUROLOGICAL DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1999-08-03 | — | — | US | disclosed |
| US-5929082-A | SULFONYL(THIO)UREA AND SULFONYLGUANIDINE COMPOUNDS; TREATMENT OF DIABETES, CARDIAC ARRHYTHMIAS, ISCHEMIA, HYPOXIC CARDIOVASCUALR DISORDERS AND CANCER | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 1999-07-27 | — | — | US | disclosed |
| EP-0819118-A4 | POTASSIUM ION CHANNEL BLOCKERS | POLYCHIP PHARMACEUTICALS PTY (AU) | 1998-04-29 | — | — | EP | disclosed |
| EP-0819118-A1 | POTASSIUM ION CHANNEL BLOCKERS | Polychip Pharmaceuticals Pty. Ltd. (AU) | 1998-01-21 | — | — | EP | disclosed |
| EP-0815861-A1 | Sulphonamides and their use | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996030341-A1 | POTASSIUM ION CHANNEL BLOCKERS | POLYCHIP PHARMACEUTICALS PTY. LTD. (AU) | 1996-10-03 | — | — | WO | disclosed |