Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545286 | 0.85 | ALDH1A1 (0.52) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL12004538 | 0.83 | GAA (0.54) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL22121183 | 0.82 | MAPT (0.54) | ALDH1A1GAAMAPTKDM4EKDM4C | |
| SCHEMBL31072837 | 0.80 | HDAC8 (0.57) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL20912613 | 0.78 | KDM4C (0.52) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL24636086 | 0.77 | APLNR (0.56) | ALDH1A1GAAHSD17B10MAPTKDM4C | |
| SCHEMBL12751066 | 0.77 | APLNR (0.50) | ALDH1A1GAAHSD17B10MAPTKDM4C | |
| SCHEMBL1265017 | 0.77 | CYP3A4 (0.52) | ALDH1A1GAAHSD17B10KDM4CAPLNR | |
| SCHEMBL1180032 | 0.77 | LOXL2 (0.53) | ALDH1A1GAAHSD17B10MAPTKDM4E | |
| SCHEMBL28091611 | 0.76 | CYP1A2 (0.58) | ALDH1A1HSD17B10KDM4CUSP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |