Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121210 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL8037980 | 0.84 | KDM4E (0.52) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL28544871 | 0.82 | HTT (0.53) | ALDH1A1GAAMAPTPTGER4HPGD | |
| SCHEMBL12004538 | 0.82 | GAA (0.54) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL4539438 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL29343403 | 0.79 | MAPT (0.49) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL31072837 | 0.79 | HDAC8 (0.57) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL4538645 | 0.77 | MAPT (0.54) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL23630654 | 0.76 | CASR (0.49) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL30181799 | 0.76 | CASR (0.49) | ALDH1A1KDM4EGAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107434789-B | Benzotriazole derivatives, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2021-04-13 | — | — | CN | disclosed |