Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124874 | 1.00 | LMNA (0.47) | LMNAMAPK1CXCL8CTSDCA12 | |
| SCHEMBL27538010 | 0.82 | SRC (0.45) | LMNAMAPK1CXCL8CTSDCA12 | |
| SCHEMBL4944935 | 0.79 | CXCL8 (0.58) | LMNAMAPK1CXCL8POLBKMT2A | |
| SCHEMBL275598 | 0.79 | LMNA (0.64) | LMNAMAPK1POLBPKMPTPN1 | |
| SCHEMBL4943731 | 0.75 | KCNQ2 (0.43) | POLBL3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL16882743 | 0.74 | LMNA (0.52) | LMNAMAPK1CA1CA2CA9 | |
| SCHEMBL17714332 | 0.74 | GRIN2D (0.39) | LMNACXCL8CA12CA1CA2 | |
| SCHEMBL5159943 | 0.74 | LMNA (0.52) | LMNAMAPK1CA1CA2CA9 | |
| SCHEMBL5159947 | 0.74 | LMNA (0.52) | LMNAMAPK1CA1CA2CA9 | |
| SCHEMBL11435906 | 0.73 | CXCL8 (0.71) | LMNAMAPK1CXCL8BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220046923-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | US | disclosed |
| EP-3898594-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| CN-113195455-A | Herbicidal cinnolinium compounds | 先正达农作物保护股份公司 | 2021-07-30 | — | — | CN | disclosed |
| WO-2020127168-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220046923-A1 | HERBICIDAL CINNOLINIUM COMPOUNDS | DDT, DERL1, CES2 | LMNA 3770/4885MAPK1 2889/4885CXCL8 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.