Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374320 | 0.81 | CYP1A1 (0.40) | LMNAMAPTSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL6688879 | 0.76 | HDAC3 (0.47) | LMNAL3MBTL1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL11368813 | 0.75 | HDAC3 (0.50) | LMNAL3MBTL1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL8407975 | 0.74 | ITGB3 (0.43) | — | |
| SCHEMBL14918867 | 0.73 | ALDH1A1 (0.48) | KMT2AMAPTSMN1; SMN2MEN1RAB9A | |
| SCHEMBL11375556 | 0.73 | KMT2A (0.47) | HSD17B10KMT2AL3MBTL1SMN1; SMN2GAA | |
| Hydroxyamine SCHEMBL7655304 | 0.72 | PDE4B (0.49) | L3MBTL1PDE4BRAB9AHDAC3HDAC4 | |
| SCHEMBL1576901 | 0.70 | MAPK1 (0.48) | KMT2ALMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL82223 | 0.70 | HSD17B10 (1.00) | HSD17B10KMT2ALMNAL3MBTL1MAPT | |
| SCHEMBL11403476 | 0.70 | CYP1A1 (0.42) | L3MBTL1GAARAB9AALDH1A1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389616-B1 | 3,4-Dihalobenzylpiperidine derivatives and their medical use | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-07-27 | — | — | EP | disclosed |
| CN-100384838-C | Novel benzylpiperidine compound | MITSUBISHI PHARMA CORP (JP) | 2008-04-30 | — | — | CN | disclosed |
| US-7115635-B2 | Benzylpiperidine compound | MITSUBISHI PHARMA CORPORATION (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20040158071-A1 | Chemokine inhibitors and stability in blood | MITSUBISHI PHARMA CORPORATION (JP) | 2004-08-12 | — | — | US | disclosed |
| CN-1505626-A | Novel benzylpiperidine compound | ������ҩ��ʽ���� | 2004-06-16 | — | — | CN | disclosed |
| EP-1389616-A1 | NOVEL BENZYLPIPERIDINE COMPOUND | Mitsubishi Pharma Corporation (JP) | 2004-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158071-A1 | Chemokine inhibitors and stability in blood | CCL2, CXCR1, CCR5 | HSD17B10 2037/4885KMT2A 3818/4885LMNA 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.