SCHEMBL22129595

SCHEMBL22129595

CC(=CCCCCCCc1ccc(Oc2ccccc2)cc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.50
PPARG P37231 2/20 0.47
TBXAS1 P24557 1/20 0.46
PLAAT3 P53816 1/20 0.45
PLAAT5 Q96KN8 1/20 0.45
PLAAT2 Q9NWW9 1/20 0.45
PLAAT4 Q9UL19 1/20 0.45
SRD5A2 P31213 2/20 0.45
FFAR4 Q5NUL3 1/20 0.44
EPHX2 P34913 1/20 0.42
MMP12 P39900 2/20 0.41
MMP13 P45452 2/20 0.41
MMP8 P22894 1/20 0.41
LTA4H P09960 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22129627 1.00 FFAR1 (0.50) FFAR1PPARGTBXAS1PLAAT3PLAAT5
SCHEMBL22129594 0.99 FFAR1 (0.51) FFAR1PPARGTBXAS1PLAAT3PLAAT5
SCHEMBL22129638 0.94 FFAR1 (0.53) FFAR1PPARGTBXAS1PLAAT3PLAAT5
SCHEMBL22129617 0.89 FFAR1 (0.55) FFAR1PPARGPLAAT3PLAAT5PLAAT2
SCHEMBL22129585 0.88 PPARA (0.51) FFAR1PPARGTBXAS1
SCHEMBL6255796 0.87 TBXAS1 (0.52) TBXAS1
SCHEMBL1122044 0.87 TBXAS1 (0.52) TBXAS1
SCHEMBL343141 0.87 TBXAS1 (0.52) TBXAS1
SCHEMBL6467606 0.87 TBXAS1 (0.52) TBXAS1
SCHEMBL1122039 0.87 TBXAS1 (0.52) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074945-A1 CURABLE COMPOSITION FOR DENTAL RESTORATION KURARAY NORITAKE DENTAL INC. (JP) 2024-03-07 US disclosed
EP-4268797-A1 CURABLE COMPOSITION FOR DENTAL RESTORATION Kuraray Noritake Dental Inc. (JP) 2023-11-01 EP disclosed
US-20220218572-A1 DENTAL RESTORATIVE CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2022-07-14 US disclosed
US-11365280-B2 Photocurable resin composition KURARAY NORITAKE DENTAL INC. (JP) 2022-06-21 US disclosed
EP-3778681-A1 PHOTOCURABLE RESIN COMPOSITION Kuraray Noritake Dental Inc. (JP) 2021-02-17 EP disclosed
US-20210024682-A1 PHOTOCURABLE RESIN COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2021-01-28 US disclosed
WO-2020129736-A1 RESIN COMPOSITION FOR OPTICAL MOLDING クラレノリタケデンタル株式会社 2020-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11365280-B2 Photocurable resin composition MAT1A, MAT2A, MAT2B FFAR1 335/4885PPARG 2822/4885TBXAS1 2818/4885
US-20210024682-A1 PHOTOCURABLE RESIN COMPOSITION MAT1A, MAT2A, MAT2B FFAR1 335/4885PPARG 2822/4885TBXAS1 2818/4885
US-20240074945-A1 CURABLE COMPOSITION FOR DENTAL RESTORATION SMCHD1, WDR26, KAT6A FFAR1 1296/4885PPARG 3074/4885TBXAS1 4522/4885
US-20220218572-A1 DENTAL RESTORATIVE CURABLE COMPOSITION REV1, MMAB, WDR1 FFAR1 1463/4885PPARG 4199/4885TBXAS1 4217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.