Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 12/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | GLA | P06280 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20357506 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2CA1CA2CA4MAPT | |
| SCHEMBL30440638 | 0.83 | DYRK1A (0.55) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4590686 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2CA1CA2CA4MAPT | |
| SCHEMBL22130133 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2CA2MAPTALDH1A1NPC1 | |
| SCHEMBL10830079 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CA1CA2CA4MAPT | |
| SCHEMBL11337470 | 0.80 | ACP1 (0.46) | SMN1; SMN2CA1CA2MAPTALDH1A1 | |
| SCHEMBL12210994 | 0.80 | LIPG (0.58) | — | |
| SCHEMBL77032 | 0.79 | KMT2A (0.68) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL2093965 | 0.79 | ACP1 (0.57) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL3251161 | 0.78 | UBE2T (0.59) | SMN1; SMN2CA1CA2CA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020130214-A1 | NOVEL HYDRAZONE DERIVATIVE WITH ARYL OR HETEROARYL GROUP SUBSTITUTED AT TERMINAL AMINE GROUP THEREOF AND USE THEREOF | 한국과학기술연구원 | 2020-06-25 | — | — | WO | disclosed |