Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.63 |
| ▸ | NT5E | P21589 | 1/20 | 0.63 |
| ▸ | KRAS | P01116 | 12/20 | 0.60 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.54 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E626 SCHEMBL22134207 | 0.91 | TGM2 (0.65) | TGM2NT5EKRASIMPDH2IMPDH1 | |
| SCHEMBL21742682 | 0.91 | NT5E (0.69) | TGM2NT5EKRASFUT5IMPDH2 | |
| SCHEMBL21742687 | 0.89 | TGM2 (0.75) | TGM2NT5EKRASFUT5 | |
| Ammonia Solution, Strong SCHEMBL21715317 | 0.85 | NT5E (0.69) | TGM2NT5EKRASFUT5IMPDH2 | |
| SCHEMBL21742747 | 0.84 | KRAS (0.72) | TGM2NT5EKRASFUT5 | |
| SCHEMBL21742888 | 0.84 | NT5E (0.70) | TGM2NT5EKRASFUT5IMPDH2 | |
| Ammonia Solution, Strong SCHEMBL22134209 | 0.84 | TGM2 (0.81) | TGM2NT5EKRASFUT5IMPDH2 | |
| Ammonia Solution, Strong SCHEMBL22134210 | 0.84 | TGM2 (0.81) | TGM2NT5EKRASFUT5IMPDH2 | |
| E626 SCHEMBL11777031 | 0.83 | NT5E (0.81) | TGM2NT5EKRASFUT5IMPDH2 | |
| Ammonia Solution, Strong SCHEMBL28001210 | 0.83 | TGM2 (0.80) | TGM2NT5EKRASFUT5IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696709-B2 | Phosphotriazole MRNA 5′-end cap analogs, composition comprising the same, RNA molecule incorporating the same, uses thereof and method of synthesizing RNA molecule, protein or peptide | UNIWERSYTET WARSZAWSKI (PL) | 2020-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696709-B2 | Phosphotriazole MRNA 5′-end cap analogs, composition comprising the same, RNA molecule incorporating the same, uses thereof and method of synthesizing RNA molecule, protein or peptide | RNGTT, RNMT, NSUN3 | TGM2 3265/4885NT5E 1027/4885KRAS 3243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.