Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22134630 | 0.84 | KCNK3 (0.55) | SMN1; SMN2KCNK3KCNK9RXFP1MAPT | |
| SCHEMBL2169790 | 0.81 | CTSD (0.62) | CTSDNPC1SMN1; SMN2STAT3GAA | |
| SCHEMBL30744822 | 0.81 | CTSD (0.62) | CTSDNPC1SMN1; SMN2STAT3GAA | |
| SCHEMBL29097533 | 0.80 | CTSD (0.60) | CTSDNPC1SMN1; SMN2STAT3GAA | |
| SCHEMBL7973351 | 0.78 | CTSD (0.63) | CTSDNPC1SMN1; SMN2STAT3GAA | |
| SCHEMBL22503203 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2GAAHPGDMAPTALDH1A1 | |
| SCHEMBL26163054 | 0.78 | HPGD (0.61) | NPC1SMN1; SMN2GAARAB9AHPGD | |
| SCHEMBL16244081 | 0.77 | KDM4E (0.62) | CTSDNPC1SMN1; SMN2STAT3GAA | |
| SCHEMBL23014667 | 0.76 | PTGS1 (0.51) | NPC1SMN1; SMN2GAARAB9AHPGD | |
| SCHEMBL18921062 | 0.76 | SMN1; SMN2 (0.51) | NPC1SMN1; SMN2GAARAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219919-A1 | LITHIUM EXTRACTION WITH CROWN ETHERS | ORCA HOLDINGS, LLC | 2023-07-13 | — | — | US | disclosed |
| US-20230219919-A1 | LITHIUM EXTRACTION WITH CROWN ETHERS | ORCA HOLDINGS, LLC | 2023-07-13 | — | — | US | disclosed |
| WO-2020131964-A1 | LITHIUM EXTRACTION WITH CROWN ETHERS | 6th Wave Innovations Corp. (US) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219919-A1 | LITHIUM EXTRACTION WITH CROWN ETHERS | LCLAT1, LCT, IGF2R | CTSD 2571/4885NPC1 583/4885SMN1; SMN2 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.