Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.62 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169790 | 1.00 | CTSD (0.62) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29097533 | 0.85 | CTSD (0.60) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7973351 | 0.83 | CTSD (0.63) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16244081 | 0.82 | KDM4E (0.62) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7983685 | 0.82 | HCRTR1 (0.65) | RAB9AKCNK3KCNK9HPGDGAA | |
| SCHEMBL366008 | 0.82 | FLT1 (0.51) | RAB9ANPC1SMN1; SMN2HPGDGAA | |
| SCHEMBL16618453 | 0.81 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2HPGDGAA | |
| SCHEMBL22134643 | 0.81 | CTSD (0.55) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30744918 | 0.80 | CTSD (0.54) | CTSDSTAT3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9414560 | 0.80 | POLB (0.68) | CTSDRAB9AGAAMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |