Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAP3K12 | Q12852 | 11/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | DLK1 | P80370 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9942448 | 0.73 | LMNA (0.41) | ALDH1A1LMNAGLAL3MBTL1MAP3K12 | |
| SCHEMBL9943626 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNAGLAL3MBTL1TEAD1 | |
| SCHEMBL9943489 | 0.63 | CLK1 (0.40) | ALDH1A1LMNAGLAL3MBTL1 | |
| SCHEMBL30834860 | 0.59 | ALDH1A1 (0.47) | ALDH1A1LMNAGLAL3MBTL1MAPK1 | |
| SCHEMBL15301848 | 0.58 | PIK3C3 (0.38) | PIK3CAMTOR | |
| SCHEMBL22135115 | 0.58 | SYK (0.39) | ALDH1A1LMNAGLAL3MBTL1MAP3K12 | |
| SCHEMBL14768765 | 0.58 | NOS3 (0.52) | ALDH1A1L3MBTL1MAPK1KIF11 | |
| SCHEMBL27482604 | 0.57 | CA2 (0.50) | ALDH1A1LMNAGLAL3MBTL1MAPK1 | |
| SCHEMBL22747550 | 0.57 | AR (0.40) | ALDH1A1L3MBTL1MAP3K12TEAD1KIF11 | |
| SCHEMBL22718250 | 0.57 | TEAD1 (0.43) | ALDH1A1L3MBTL1MAP3K12TEAD1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3669874-A1 | QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF CANCER | ABIVAX (FR) | 2020-06-24 | — | — | EP | disclosed |