SCHEMBL22140249

SCHEMBL22140249

C=CCOc1cc(F)ccc1C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 12/20 0.46
HTR2A P28223 8/20 0.46
MAPT P10636 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
HTR2B P41595 7/20 0.38
ADRA2A P08913 3/20 0.38
ADRA2B P18089 3/20 0.38
ADRA2C P18825 3/20 0.38
ADRB2 P07550 2/20 0.38
HTR1A P08908 2/20 0.38
CHRM5 P08912 2/20 0.38
DRD2 P14416 2/20 0.38
DRD4 P21917 2/20 0.38
HRH2 P25021 2/20 0.38
SLC6A4 P31645 2/20 0.38
HTR7 P34969 2/20 0.38
DRD3 P35462 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22140449 0.82 HTT (0.49) MAPTL3MBTL1MEN1HTTKMT2A
SCHEMBL22215852 0.81 MEN1 (0.43) HTR2CHTR2AMEN1HTTKMT2A
SCHEMBL22140285 0.81 GAA (0.50) HTR2CHTR2AMEN1HTTKMT2A
SCHEMBL22140447 0.81 MEN1 (0.56) HTR2CHTR2AL3MBTL1MEN1HTT
SCHEMBL17955432 0.80 L3MBTL1 (0.42) MAPTL3MBTL1MEN1HTTKMT2A
SCHEMBL17688869 0.80 RBP4 (0.39) L3MBTL1HTTDRD2HTR7HSD17B10
SCHEMBL7749472 0.80 HSD17B10 (0.47) HTR2AMAPTHTTADRA2AADRA2B
SCHEMBL21728215 0.78 MAPT (0.47) HTR2CHTR2AMAPTL3MBTL1HTR2B
SCHEMBL3885806 0.78 HTR2C (0.49) HTR2CHTR2AMAPTL3MBTL1MEN1
SCHEMBL7623243 0.78 MAPT (0.49) HTR2CHTR2AMAPTL3MBTL1HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11000038-B2 Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients MITSUI CHEMICALS AGRO, INC. (JP) 2021-05-11 US disclosed
US-20200196600-A1 PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS MITSUI CHEMICALS AGRO, INC. (JP) 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200196600-A1 PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS PNPO, PDXK, PLPBP HTR2C 1690/4885HTR2A 1338/4885MAPT 2876/4885
US-11000038-B2 Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients PNPO, PDXK, PLPBP HTR2C 1690/4885HTR2A 1338/4885MAPT 2876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.