Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796001 | 0.87 | CA1 (0.47) | CA2CA1PTGS2SHBGCYP3A4 | |
| SCHEMBL10953728 | 0.82 | CA2 (0.64) | CA2CA1PTGS2CYP3A4ALDH1A1 | |
| SCHEMBL221405 | 0.80 | ALDH1A1 (0.51) | CA2CA1SHBGCYP3A4ALDH1A1 | |
| SCHEMBL9332354 | 0.79 | SHBG (0.48) | CA2CA1SHBGCYP3A4ALDH1A1 | |
| SCHEMBL5080349 | 0.79 | CA1 (0.60) | CA2CA1PTGS2CYP3A4ALDH1A1 | |
| SCHEMBL9328910 | 0.78 | SHBG (0.40) | CA2CA1SHBGCYP3A4ALDH1A1 | |
| SCHEMBL9455663 | 0.78 | CA2 (0.75) | CA2CA1PTGS2CYP3A4ALDH1A1 | |
| SCHEMBL226090 | 0.78 | ALDH1A1 (0.58) | CA2CA1PTGS2SHBGCYP3A4 | |
| SCHEMBL767213 | 0.78 | SHBG (0.52) | CA2CA1SHBGCYP3A4ALDH1A1 | |
| SCHEMBL9652029 | 0.78 | CA1 (0.53) | CA2CA1PTGS2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125531-A1 | Polymerizable Composition, Thermoplastic Resin Composition, Crosslinked Resin, And Crosslinked Resin Composite Materials | ZEON COROPRATION (JP) | 2008-05-29 | — | — | US | disclosed |
| EP-1589054-A1 | POLYMERIZABLE COMPOSITION, THERMOPLASTIC RESIN COMPOSITION, CROSSLINKED RESIN, AND CROSSLINKED RESIN COMPOSITE MATERIALS | Zeon Corporation (JP) | 2005-10-26 | — | — | EP | disclosed |