Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220752 | 0.79 | SIGMAR1 (0.51) | — | |
| SCHEMBL4419316 | 0.79 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BACHE | |
| SCHEMBL7986523 | 0.76 | — | — | |
| SCHEMBL7986385 | 0.76 | ADRA1D (0.70) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6345018 | 0.74 | SIGMAR1 (0.60) | — | |
| SCHEMBL3873216 | 0.72 | MAPK1 (0.52) | — | |
| SCHEMBL3759156 | 0.71 | CASP3 (0.49) | — | |
| SCHEMBL3757316 | 0.70 | GLS (0.49) | — | |
| SCHEMBL11632652 | 0.69 | NPSR1 (0.67) | ADRA1DADRA1AADRA1B | |
| SCHEMBL4419110 | 0.69 | ADRA1D (0.64) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088925-B2 | low molecular weight factor Xa specific blood clotting inhibitors; less side effects; 5-Chloro-thiophene-2-carboxylic acid [2-(1-isopropyl-piperidin-4-ylsulfamoyl)-ethyl]-amide; thromboembolic diseases or restenosis; antithrombotic agents | SANOFI-AVENTIS (FR) | 2012-01-03 | — | — | US | disclosed |