Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000270 | 0.98 | KEAP1 (0.57) | KEAP1CES2CES1PKMHSD17B10 | |
| Hydrochloric Acid SCHEMBL1372131 | 0.98 | KEAP1 (0.57) | KEAP1CES2CES1PKMHSD17B10 | |
| SCHEMBL29280607 | 0.83 | CES2 (0.50) | KEAP1CES2CES1PKMANO1 | |
| SCHEMBL111637 | 0.83 | KEAP1 (0.53) | KEAP1CES2CES1PKMHSD17B10 | |
| SCHEMBL2523960 | 0.81 | DGAT1 (0.50) | KEAP1CES2CES1PKMANO1 | |
| SCHEMBL4649267 | 0.81 | CES2 (0.47) | KEAP1CES2CES1PKMANO1 | |
| SCHEMBL31315010 | 0.81 | CES2 (0.47) | KEAP1CES2CES1PKMANO1 | |
| SCHEMBL29847023 | 0.81 | F2R (0.48) | KEAP1CES2CES1PKMANO1 | |
| SCHEMBL485712 | 0.81 | F2R (0.48) | KEAP1CES2CES1PKMANO1 | |
| SCHEMBL336978 | 0.79 | KEAP1 (0.65) | KEAP1CES2CES1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569654-A | 9-Aminoacridine compound with multi-electron-withdrawing substituent, and preparation method and application thereof | 郑州大学 | 2025-03-07 | — | — | CN | claimed |
| CN-119285635-A | Synthesis of 8H-indolo [3,2,1-DE ] phenanthridine-8-ketone compound from carbazole and o-bromobenzoic acid and synthesis method thereof | 陕西科技大学 | 2025-01-10 | — | — | CN | claimed |
| CN-118955276-A | Preparation method of 2-bromo-5-hydroxybenzoic acid | 舞阳威森生物医药有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-117756766-A | 3-hydroxy-8-fluoro-6H-benzo [ c ] chromen-6-one derivative, and preparation method and application thereof | 常州大学 | 2024-03-26 | — | — | CN | claimed |
| CN-116396159-A | Synthesis method of 2,2' -biphenyl dicarboxylic acid compound | 湖南大学 | 2023-07-07 | — | — | CN | claimed |
| CN-1328996-A | Preparation of 2,4-dibromo-5-fluorobenzonitrile and 2,4-dibromo-5-fluorobenzoic acid by using ammonia oxidation process | UNIV WUHAN (CN) | 2002-01-02 | — | — | CN | claimed |
| EP-0647614-B1 | Process for the préparation of 5-fluoro anthranilic acid | HOECHST AG (DE) | 1997-06-04 | — | — | EP | claimed |
| US-5523472-A | Process for the preparation of 5-fluoroanthranilic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-06-04 | — | — | US | claimed |
| EP-0647614-A1 | Process for the préparation of 5-fluoro anthranilic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-12 | — | — | EP | claimed |
| JP-7165687-A | — | — | None | — | — | JP | disclosed |
| CN-117164587-B | Ester group-containing substituted evodiamine derivative, preparation method and application | 南华大学附属第一医院 | 2026-05-12 | — | — | CN | disclosed |
| US-20260116868-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2026-04-30 | — | — | US | disclosed |
| US-12606522-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | ORSOBIO, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| US-20260085070-A1 | HETEROCYCLIC CBL-B INHIBITORS FOR THE TREATMENT OF CANCER | HOTSPOT THERAPEUTICS INC (US) | 2026-03-26 | — | — | US | disclosed |
| JP-H07165687-A | PREPARATION OF 5-FLUOROANTHRANILIC ACID | HOECHST AG | 1995-06-27 | — | — | JP | disclosed |
| WO-1995016682-A1 | CYCLIC AMIDE DERIVATIVES AS NEUROKININ A ANTAGONISTS | ZENECA LIMITED (GB) | 1995-06-22 | — | — | WO | disclosed |
| EP-0647614-A1 | Process for the préparation of 5-fluoro anthranilic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0647614-A1 | Process for the préparation of 5-fluoro anthranilic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-12 | — | — | EP | disclosed |
| US-3987186-A | ANTIALLERGENS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-10-19 | — | — | US | disclosed |
| US-3953595-A | Substituted benzoic acid hypolipemic agents | PFIZER INC. (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085070-A1 | HETEROCYCLIC CBL-B INHIBITORS FOR THE TREATMENT OF CANCER | CBL, CBLB, CBLC | KEAP1 964/4885CES2 2022/4885CES1 304/4885 |
| US-20260116868-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | CBLB, CBLC, CBL | KEAP1 358/4885CES2 1088/4885CES1 148/4885 |
| US-12606522-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | NR3C2, NR5A1, SRD5A2 | KEAP1 2573/4885CES2 526/4885CES1 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.