Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729341 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL31728628 | 0.78 | PKM (0.42) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL31649970 | 0.78 | GRM5 (0.40) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL31729030 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1GAAGLALMNA | |
| SCHEMBL5262211 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL31728257 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1GAAGLALMNA | |
| SCHEMBL6469168 | 0.71 | ADORA3 (0.57) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL259599 | 0.69 | KDM4E (0.51) | KDM4EALDH1A1GAAGLALMNA | |
| SCHEMBL259043 | 0.69 | KDM4E (0.50) | KDM4EALDH1A1GAAMPIHPGD | |
| Hydrochloric Acid SCHEMBL6445246 | 0.69 | ADORA3 (0.55) | KDM4EALDH1A1GAAGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132561-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |