Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13370818 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL18459228 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL17224054 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL18575691 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL13370816 | 0.80 | KLK7 (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL12146430 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL12203139 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL14276910 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL31728257 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL24242399 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008754-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | UNIV MEDYCZNY W LUBLINIE (PL) | 2026-01-08 | — | — | US | claimed |
| EP-4652156-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | Uniwersytet Medyczny w Lublinie (PL) | 2025-11-26 | — | — | EP | claimed |
| WO-2024117922-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | UNIWERSYTET MEDYCZNY W LUBLINIE (PL) | 2024-06-06 | — | — | WO | claimed |
| US-20260008754-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | UNIV MEDYCZNY W LUBLINIE (PL) | 2026-01-08 | — | — | US | disclosed |
| US-20260008754-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | UNIV MEDYCZNY W LUBLINIE (PL) | 2026-01-08 | — | — | US | disclosed |
| EP-4652156-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | Uniwersytet Medyczny w Lublinie (PL) | 2025-11-26 | — | — | EP | disclosed |
| EP-4652156-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | Uniwersytet Medyczny w Lublinie (PL) | 2025-11-26 | — | — | EP | disclosed |
| US-20240208952-A1 | THIOPHENE GLP-1 RECEPTOR AGONIST AND USE THEREOF | HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) | 2024-06-27 | — | — | US | disclosed |
| US-20240208952-A1 | THIOPHENE GLP-1 RECEPTOR AGONIST AND USE THEREOF | HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO., LTD. (CN) | 2024-06-27 | — | — | US | disclosed |
| WO-2024117922-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | UNIWERSYTET MEDYCZNY W LUBLINIE (PL) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024117922-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | UNIWERSYTET MEDYCZNY W LUBLINIE (PL) | 2024-06-06 | — | — | WO | disclosed |
| US-20120135987-A1 | NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS | H. LUNDBECK A/S (DK) | 2012-05-31 | — | — | US | disclosed |
| US-8133897-B2 | Phenylimidazole derivatives as PDE10A enzyme inhibitors | H. LUNDBECK A/S (DK) | 2012-03-13 | — | — | US | disclosed |
| EP-1697312-B1 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA AS (DK) | 2011-07-20 | — | — | EP | disclosed |
| US-20100016303-A1 | NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS | H. LUNDBECK A/S (DK) | 2010-01-21 | — | — | US | disclosed |
| US-20080275235-A1 | NOVEL FUSED HETEROAROMATIC COMPOUNDS AS TRANSFORMING GROWTH FACTOR (TGF) INHIBITORS | PFIZER INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-7417041-B2 | Imidazopyrimidines as transforming growth factor (TGF) inhibitors | PFIZER INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-7326705-B2 | Heterocyclic sodium/proton exchange inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |
| WO-2008003511-A1 | USE OF AMINOTHIAZOLE DERIVATIVE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, IN THE TREATMENT OF DISEASES CHARACTERIZED BY ABNORMAL REPRESSION OF GENE TRANSCRIPTION, PARTICULARLY HUNTINGTON'S DISEASE | DIALECTICA S.R.L. (IT) | 2008-01-10 | — | — | WO | disclosed |
| US-7196095-B2 | (Pyrimidinyl) (phenyl) substituted fused heteroaryl p38 inhibiting and PKG kinase inhibiting compounds | MERCK & CO., INC. (US) | 2007-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016303-A1 | NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS | PDE10A, PDE5A, PDE3B | KDM4E 356/4885ALDH1A1 65/4885HPGD 1196/4885 |
| US-20120135987-A1 | NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS | PDE10A, PDE5A, PDE3B | KDM4E 356/4885ALDH1A1 65/4885HPGD 1196/4885 |
| US-20240208952-A1 | THIOPHENE GLP-1 RECEPTOR AGONIST AND USE THEREOF | GLP1R, GIPR, GCGR | KDM4E 2930/4885ALDH1A1 2375/4885HPGD 2741/4885 |
| US-20260008754-A1 | N-SUBSTITUTED DERIVATIVES OF L-(L-PHENYL-3-ARYL)-LFF-PYRAZOL-4-YL)METHANAININE, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATIONS | HTR1F, ADH5, HRH4 | KDM4E 1214/4885ALDH1A1 1035/4885HPGD 421/4885 |
| US-20080275235-A1 | NOVEL FUSED HETEROAROMATIC COMPOUNDS AS TRANSFORMING GROWTH FACTOR (TGF) INHIBITORS | TGFBR1, SMAD3, SMAD2 | KDM4E 1485/4885ALDH1A1 1680/4885HPGD 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.