Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 3/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18396986 | 0.85 | NNMT (0.44) | NNMTCYP2A6NOS3NOS1NOS2 | |
| SCHEMBL26144367 | 0.85 | NNMT (0.42) | NNMTCYP2A6DHFRLOXLOXL2 | |
| SCHEMBL10263430 | 0.82 | NOS3 (0.55) | NNMTCYP2A6NOS3NOS1NOS2 | |
| SCHEMBL6794136 | 0.81 | TUBB4A (0.39) | NNMTLOXLOXL2SLC6A2SLC6A4 | |
| SCHEMBL30987534 | 0.81 | NNMT (0.46) | NNMTCYP2A6NOS3NOS1NOS2 | |
| SCHEMBL22145148 | 0.81 | NNMT (0.50) | NNMTCYP2A6NOS3NOS1NOS2 | |
| SCHEMBL21327094 | 0.81 | NNMT (0.50) | NNMTCYP2A6NOS3NOS1NOS2 | |
| SCHEMBL22122764 | 0.79 | HTR1A (0.34) | NNMTDHFRLOXLOXL2GABRP | |
| SCHEMBL9013521 | 0.77 | NNMT (0.35) | NNMTLOXLOXL2MEN1KMT2A | |
| SCHEMBL30486638 | 0.77 | NNMT (0.35) | NNMTLOXLOXL2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127508-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |