Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 18/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22627436 | 1.00 | FKBP1A (0.74) | FKBP1A | |
| SCHEMBL17920593 | 0.92 | FKBP1A (0.65) | FKBP1A | |
| SCHEMBL17920611 | 0.92 | FKBP1A (0.65) | FKBP1A | |
| SCHEMBL22627521 | 0.92 | FKBP1A (0.81) | FKBP1A | |
| SCHEMBL24168390 | 0.92 | FKBP1A (0.81) | FKBP1A | |
| SCHEMBL17921877 | 0.90 | FKBP1A (0.77) | FKBP1A | |
| SCHEMBL17921909 | 0.90 | FKBP1A (0.77) | FKBP1A | |
| SCHEMBL5966132 | 0.85 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL22627522 | 0.84 | FKBP1A (0.65) | FKBP1A | |
| SCHEMBL22840762 | 0.82 | FKBP1A (0.67) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199102-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199102-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | PIN1, FKBP14, FKBP2 | FKBP1A 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.