Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22146706 | 0.90 | MAOB (0.44) | MAOBHTTHTR2BCES1SLC6A2 | |
| SCHEMBL4068688 | 0.84 | SRD5A1 (0.55) | MAOBHTTHTR2BSRD5A1SRD5A2 | |
| SCHEMBL8859036 | 0.84 | CES1 (0.56) | MAOBHTTHTR2BCES1CYP19A1 | |
| SCHEMBL4036590 | 0.83 | HTT (0.44) | MAOBHTTHTR2BSRD5A1SRD5A2 | |
| SCHEMBL4161951 | 0.83 | HTT (0.44) | MAOBHTTHTR2BSRD5A1SRD5A2 | |
| SCHEMBL4036595 | 0.83 | HTT (0.44) | MAOBHTTHTR2BSRD5A1SRD5A2 | |
| SCHEMBL4135475 | 0.81 | CES1 (0.61) | MAOBHTTSRD5A1SRD5A2CES1 | |
| SCHEMBL4159260 | 0.80 | HTR2B (0.47) | HTTHTR2BSRD5A1SRD5A2SLC6A2 | |
| SCHEMBL4159257 | 0.80 | HTR2B (0.47) | HTTHTR2BSRD5A1SRD5A2SLC6A2 | |
| SCHEMBL11097918 | 0.80 | HTT (0.41) | MAOBHTTHTR2BSRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200200765-A1 | BROAD SPECTRUM GPCR BINDING AGENTS | PROMEGA CORPORATION | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200200765-A1 | BROAD SPECTRUM GPCR BINDING AGENTS | GPR139, GPR4, GPR3 | MAOB 1967/4885HTT 4282/4885HTR2B 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.