Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14537027 | 1.00 | TBXAS1 (0.48) | TBXAS1FDPSPKMKMT2ANAPRT | |
| SCHEMBL13957293 | 0.88 | TBXAS1 (0.55) | TBXAS1FDPSPKMKMT2ANAPRT | |
| SCHEMBL14511421 | 0.87 | TBXAS1 (0.47) | TBXAS1FDPSPKMKMT2ANAPRT | |
| SCHEMBL13934329 | 0.85 | TBXAS1 (0.50) | TBXAS1FDPSPKMKMT2ANAPRT | |
| SCHEMBL14898388 | 0.85 | TBXAS1 (0.50) | TBXAS1FDPSPKMKMT2ANAPRT | |
| SCHEMBL12220088 | 0.85 | TBXAS1 (0.50) | TBXAS1FDPSPKMKMT2ANAPRT | |
| SCHEMBL13154997 | 0.81 | FDPS (0.47) | TBXAS1FDPSPKMKMT2ANAPRT | |
| SCHEMBL16252309 | 0.81 | LMNA (0.53) | PKMLMNACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL13233695 | 0.81 | LMNA (0.53) | PKMLMNACYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL14864793 | 0.80 | NLRP3 (0.48) | TBXAS1FDPSPKMKMT2ANAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020131283-A1 | ANALOGS THAT TARGET MITOCHONDRIAL DISEASES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |