Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26429862 | 0.87 | KMT2A (0.39) | LMNAHPGDCYP3A4L3MBTL1KMT2A | |
| SCHEMBL18659591 | 0.77 | ALOX15 (0.43) | LMNAL3MBTL1KMT2AACACBMEN1 | |
| SCHEMBL10477398 | 0.77 | CYP3A4 (0.42) | HPGDCYP3A4L3MBTL1KMT2AACACB | |
| SCHEMBL10637181 | 0.76 | CYP3A4 (0.44) | HPGDCYP3A4KMT2APOLBSMN1; SMN2 | |
| SCHEMBL10637176 | 0.76 | CYP3A4 (0.44) | HPGDCYP3A4KMT2APOLBSMN1; SMN2 | |
| SCHEMBL10636928 | 0.76 | CYP3A4 (0.41) | HPGDCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL10636921 | 0.76 | CYP3A4 (0.41) | HPGDCYP3A4KMT2AMEN1TSHR | |
| SCHEMBL13254073 | 0.70 | OPRM1 (0.37) | — | |
| SCHEMBL26428476 | 0.70 | OPRM1 (0.37) | — | |
| SCHEMBL21062348 | 0.69 | SLC7A5 (0.46) | KMT2AMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020131283-A1 | ANALOGS THAT TARGET MITOCHONDRIAL DISEASES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |