Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22147479 | 0.87 | LMNA (0.40) | KMT2AHPGDCYP3A4LMNAL3MBTL1 | |
| SCHEMBL26428476 | 0.84 | OPRM1 (0.37) | — | |
| SCHEMBL13254073 | 0.84 | OPRM1 (0.37) | — | |
| SCHEMBL10637181 | 0.75 | CYP3A4 (0.44) | KMT2AHPGDCYP3A4SMN1; SMN2 | |
| SCHEMBL10636921 | 0.75 | CYP3A4 (0.41) | KMT2AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL10636928 | 0.75 | CYP3A4 (0.41) | KMT2AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL10637176 | 0.75 | CYP3A4 (0.44) | KMT2AHPGDCYP3A4SMN1; SMN2 | |
| SCHEMBL16171769 | 0.74 | LDHA (0.43) | KMT2AALDH1A1 | |
| SCHEMBL10477398 | 0.72 | CYP3A4 (0.42) | KMT2AHPGDCYP3A4L3MBTL1MTNR1A | |
| SCHEMBL18659591 | 0.72 | ALOX15 (0.43) | KMT2ALMNAL3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069549-A1 | METHODS AND COMPOSITIONS COMPRISING PEPTIDOMIMITICS FOR TREATING, PREVENTING, INHIBITING, AMELIORATING OR DELAYING THE ONSET OF OPHTHALMIC CONDITIONS | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-04-27 | — | — | WO | disclosed |