SCHEMBL26428476

SCHEMBL26428476

Cc1cc(O)cc(C)c1C[C@@H](NC(C)C)C(=O)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 7/20 0.37
OPRD1 P41143 5/20 0.35
OPRK1 P41145 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13254073 1.00 OPRM1 (0.37) OPRM1OPRD1OPRK1
SCHEMBL26429862 0.84 KMT2A (0.39)
SCHEMBL13254076 0.81 HSP90AB1 (0.40) OPRM1
SCHEMBL25469825 0.76 OPRK1 (0.46) OPRM1OPRD1OPRK1
SCHEMBL27250348 0.74 FOLH1 (0.49)
SCHEMBL7601953 0.74 FOLH1 (0.49)
SCHEMBL15185807 0.73 CTSS (0.36) OPRD1
SCHEMBL12411251 0.73 CTSS (0.36) OPRD1
SCHEMBL18855074 0.73 TAS1R3 (0.38)
SCHEMBL25460710 0.73 HPGD (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023069549-A1 METHODS AND COMPOSITIONS COMPRISING PEPTIDOMIMITICS FOR TREATING, PREVENTING, INHIBITING, AMELIORATING OR DELAYING THE ONSET OF OPHTHALMIC CONDITIONS STEALTH BIOTHERAPEUTICS INC. (US) 2023-04-27 WO disclosed