Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978302 | 0.89 | ALOX5 (0.54) | CCR6PAX8ALOX5LTA4HALDH1A1 | |
| SCHEMBL11928331 | 0.89 | CCR6 (0.49) | CCR6PAX8ALOX5LTA4HALDH1A1 | |
| SCHEMBL16488805 | 0.88 | CCR6 (0.47) | CCR6PAX8ALOX5LTA4HALDH1A1 | |
| SCHEMBL3423094 | 0.87 | ALOX5 (0.51) | CCR6PAX8ALOX5LTA4HALDH1A1 | |
| SCHEMBL15194247 | 0.86 | CCR6 (0.48) | CCR6PAX8ALOX5LTA4HALDH1A1 | |
| SCHEMBL15275367 | 0.86 | CCR6 (0.45) | CCR6PAX8ALOX5LTA4HALDH1A1 | |
| SCHEMBL11307171 | 0.85 | ALDH1A1 (0.47) | CCR6PAX8ALOX5LTA4HALDH1A1 | |
| SCHEMBL10058216 | 0.85 | CCR6 (0.58) | CCR6PAX8ALOX5LTA4HL3MBTL1 | |
| Hydrochloric Acid SCHEMBL15266733 | 0.85 | CCR6 (0.44) | CCR6PAX8ALOX5LTA4HALDH1A1 | |
| SCHEMBL417432 | 0.84 | CCR6 (0.57) | CCR6PAX8ALOX5LTA4HL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877961-B2 | Bridged monobactam intermediates | BASILEA PHARMACEUTICA AG (CH) | 2014-11-04 | — | — | US | disclosed |
| US-20130274503-A1 | PROCESS FOR THE MANUFACTURE OF BRIDGED MONOBACTAM INTERMEDIATES | BASILEA PHARMACEUTICA AG (CH) | 2013-10-17 | — | — | US | disclosed |
| US-8450477-B2 | Process for the manufacture of bridged monobactam intermediates | Basilea Pharmaceutica A.G. (CH) | 2013-05-28 | — | — | US | disclosed |
| EP-2197881-B1 | PROCESS FOR THE MANUFACTURE OF BRIDGED MONOBACTAM INTERMEDIATES | BASILEA PHARMACEUTICA AG (CH) | 2013-04-17 | — | — | EP | disclosed |
| US-20110178291-A1 | Process for the manufacture of bridged monobactam intermediates | Basilea Pharmacuetica AG | 2011-07-21 | — | — | US | disclosed |
| EP-2197881-A1 | PROCESS FOR THE MANUFACTURE OF BRIDGED MONOBACTAM INTERMEDIATES | Basilea Pharmaceutica AG (CH) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009037229-A1 | PROCESS FOR THE MANUFACTURE OF BRIDGED MONOBACTAM INTERMEDIATES | BASILEA PHARMACEUTICA AG (CH) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274503-A1 | PROCESS FOR THE MANUFACTURE OF BRIDGED MONOBACTAM INTERMEDIATES | COASY, ACMSD, BPGM | CCR6 753/4885PAX8 4799/4885ALOX5 763/4885 |
| US-20110178291-A1 | Process for the manufacture of bridged monobactam intermediates | C1S, CCNB1, C9 | CCR6 477/4885PAX8 4835/4885ALOX5 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.