Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 5/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.44 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963771 | 0.67 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1877773 | 0.67 | GRIN2D (0.42) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL23929750 | 0.62 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3381958 | 0.62 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL24236 | 0.62 | — | — | |
| SCHEMBL148421 | 0.61 | PKM (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL179945 | 0.61 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Amantadine SCHEMBL21309814 | 0.61 | GRIN1 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Amantadine SCHEMBL21310017 | 0.61 | GRIN1 (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8680357 | 0.61 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024263819-A2 | BORON-CONTAINING COMPOUNDS AND METHODS OF PREPARATION AND APPLICATIONS THEREOF | THE TRUSTEES OF BOSTON COLLEGE (US) | 2024-12-26 | — | — | WO | claimed |
| CN-1190406-C | Preparation method of ortho-alkylated benzoic acid derivative | MERCK PATENT GMBH (DE) | 2005-02-23 | — | — | CN | claimed |
| EP-1098866-B1 | METHOD FOR PRODUCING ORTHO-ALKYLATED BENZOIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-02-11 | — | — | EP | claimed |
| US-20030069444-A1 | METHOD FOR PRODUCING ORTHO-ALKYLATED BENZOIC ACID DERIVATIVES | MERCK KGAA (DE) | 2003-04-10 | — | — | US | claimed |
| JP-2002521352-A | — | — | 2002-07-16 | — | — | JP | claimed |
| US-20020091286-A1 | Method for producing ortho-alkylated benzoic acid derivatives | MERCK GMBH (DE) | 2002-07-11 | — | — | US | claimed |
| US-6350904-B1 | CATALYTIC CARBOXYLATION OF HALOALKYLBENZENE | MERCK KGAA (DE) | 2002-02-26 | — | — | US | claimed |
| CN-1310700-A | Preparation method of ortho-alkylated benzoic acid derivative | MERCK PATENT GMBH (DE) | 2001-08-29 | — | — | CN | claimed |
| EP-1098866-A1 | METHOD FOR PRODUCING ORTHO-ALKYLATED BENZOIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-05-16 | — | — | EP | claimed |
| WO-2000005187-A1 | METHOD FOR PRODUCING ORTHO-ALKYLATED BENZOIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-03 | — | — | WO | claimed |
| WO-2024263819-A3 | BORON-CONTAINING COMPOUNDS AND METHODS OF PREPARATION AND APPLICATIONS THEREOF | THE TRUSTEES OF BOSTON COLLEGE (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2024263819-A2 | BORON-CONTAINING COMPOUNDS AND METHODS OF PREPARATION AND APPLICATIONS THEREOF | THE TRUSTEES OF BOSTON COLLEGE (US) | 2024-12-26 | — | — | WO | disclosed |
| WO-2024263819-A2 | BORON-CONTAINING COMPOUNDS AND METHODS OF PREPARATION AND APPLICATIONS THEREOF | THE TRUSTEES OF BOSTON COLLEGE (US) | 2024-12-26 | — | — | WO | disclosed |
| US-9840465-B2 | Antiviral compounds | UNIV BRIGHAM YOUNG (US) | 2017-12-12 | — | — | US | disclosed |
| WO-2016098016-A1 | PROCESS FOR THE PREPARATION OF SGLT2 INHIBITORS | DR. REDDY’S LABORATORIES LIMITED (IN) | 2016-06-23 | — | — | WO | disclosed |
| EP-1098866-A1 | METHOD FOR PRODUCING ORTHO-ALKYLATED BENZOIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-05-16 | — | — | EP | disclosed |
| US-6046350-A | Tertiary alkylsilane | NIPPON OIL CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| WO-2000005187-A1 | METHOD FOR PRODUCING ORTHO-ALKYLATED BENZOIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-03 | — | — | WO | disclosed |
| EP-0922706-A2 | Tertiary alkylsilane | NIPPON OIL CO. LTD. (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5599998-A | DEHALOGENATION WITH LITHIUM FORMING THE CHEMICAL INTERMEDIATES | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1997-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091286-A1 | Method for producing ortho-alkylated benzoic acid derivatives | AOC2, OXER1, GABBR2 | GRIN2D 2697/4885GRIN3B 3264/4885GRIN1 3568/4885 |
| US-20030069444-A1 | METHOD FOR PRODUCING ORTHO-ALKYLATED BENZOIC ACID DERIVATIVES | AOC2, OXER1, GABBR2 | GRIN2D 2697/4885GRIN3B 3264/4885GRIN1 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.