Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 6/20 | 0.37 |
| ▸ | HPD | P32754 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149064 | 0.90 | SRC (0.41) | DOT1LKDRHPDMGLLSRC | |
| SCHEMBL22149000 | 0.88 | KDR (0.36) | KDRHPDPDGFRAMGLLSRC | |
| SCHEMBL22149092 | 0.88 | MGLL (0.39) | DOT1LKDRMGLLTGFBR1DDR2 | |
| SCHEMBL22149005 | 0.85 | TTR (0.40) | KDRHPDPDGFRASRCTGFBR1 | |
| SCHEMBL22149076 | 0.85 | KDR (0.48) | KDRPDGFRADDR2 | |
| SCHEMBL22149107 | 0.84 | SRC (0.42) | KDRHPDPDGFRASRCTGFBR1 | |
| SCHEMBL22149095 | 0.83 | SRC (0.40) | DOT1LKDRHPDPDGFRASRC | |
| SCHEMBL22149057 | 0.82 | SRC (0.41) | KDRHPDSRCTGFBR1GPBAR1 | |
| SCHEMBL22149001 | 0.81 | MET (0.50) | KDRPDGFRASRCDDR2 | |
| SCHEMBL22149056 | 0.80 | GPBAR1 (0.40) | KDRSRCTGFBR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |