Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 7/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149002 | 0.92 | MGLL (0.41) | MGLLDOT1LKDRTGFBR1DDR2 | |
| SCHEMBL22149093 | 0.89 | MGLL (0.39) | MGLLKDRTGFBR1DDR2MET | |
| SCHEMBL22148992 | 0.88 | DOT1L (0.40) | MGLLDOT1LKDRTGFBR1DDR2 | |
| SCHEMBL22149084 | 0.88 | MGLL (0.37) | MGLLKDRMETAXLMERTK | |
| SCHEMBL22149103 | 0.86 | TGFBR1 (0.38) | MGLLKDRTGFBR1DDR2MET | |
| SCHEMBL22149058 | 0.85 | MGLL (0.39) | MGLLTGFBR1METAXLMERTK | |
| SCHEMBL22149065 | 0.84 | MET (0.49) | MGLLKDRDDR2METAXL | |
| SCHEMBL22149061 | 0.83 | GPBAR1 (0.37) | MGLLKDRTGFBR1METAXL | |
| SCHEMBL22149094 | 0.82 | PDGFRA (0.41) | MGLLKDRMETAXLMERTK | |
| SCHEMBL22148987 | 0.81 | MGLL (0.41) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |