Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.51 |
| ▸ | AXL | P30530 | 13/20 | 0.51 |
| ▸ | MERTK | Q12866 | 9/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HCK | P08631 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149101 | 0.90 | KDR (0.43) | METAXLMERTKKDRPDGFRA | |
| SCHEMBL22149080 | 0.89 | PDGFRA (0.41) | METAXLMERTKKDRPDGFRA | |
| SCHEMBL22149059 | 0.87 | MET (0.38) | METAXLMERTKKDRSRC | |
| SCHEMBL22149082 | 0.85 | MET (0.36) | METAXLMERTKKDRPDGFRA | |
| SCHEMBL22149060 | 0.84 | SRC (0.37) | METAXLMERTKKDRSRC | |
| SCHEMBL22149104 | 0.83 | SRC (0.40) | METAXLMERTKKDRPDGFRA | |
| SCHEMBL22149148 | 0.83 | SRC (0.38) | METAXLMERTKKDREGFR | |
| SCHEMBL22149145 | 0.82 | RXRA (0.34) | METAXLMERTK | |
| SCHEMBL22149088 | 0.82 | DOT1L (0.37) | METAXLMERTKKDRPDGFRA | |
| SCHEMBL22148990 | 0.81 | IDO1 (0.35) | METAXLMERTKRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |