SCHEMBL22149104 — predicted protein targets

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	SRC	P12931	5/20	0.40

▸	TGFBR1	P36897	5/20	0.40

▸	MET	P08581	2/20	0.35

▸	AXL	P30530	2/20	0.35

▸	MERTK	Q12866	2/20	0.35

▸	PDGFRA	P16234	2/20	0.34

▸	RET	P07949	1/20	0.34

▸	KDR	P35968	1/20	0.34

▸	DDR2	Q16832	1/20	0.34

▸	KDM4C	Q9H3R0	1/20	0.34

▸	ACHE	P22303	1/20	0.34

▸	FGFR2	P21802	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	BTK	Q06187	1/20	0.33

▸	NOTUM	Q6P988	1/20	0.33

▸	KIT	P10721	1/20	0.33

▸	GCGR	P47871	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22149059	0.89	MET (0.38)	SRCTGFBR1METAXLMERTK
SCHEMBL22149148	0.89	SRC (0.38)	SRCTGFBR1METAXLMERTK
SCHEMBL22149060	0.87	SRC (0.37)	SRCTGFBR1METAXLMERTK
SCHEMBL22149080	0.84	PDGFRA (0.41)	METAXLMERTKPDGFRAKDR
SCHEMBL22148994	0.83	MET (0.51)	SRCMETAXLMERTKPDGFRA
SCHEMBL22149088	0.83	DOT1L (0.37)	SRCTGFBR1METAXLMERTK
SCHEMBL22149082	0.83	MET (0.36)	SRCTGFBR1METAXLMERTK
SCHEMBL22148999	0.82	TTR (0.39)	METAXLMERTKPDGFRAKDR
SCHEMBL22149101	0.82	KDR (0.43)	METAXLMERTKPDGFRAKDR
SCHEMBL22149083	0.80	SLC22A12 (0.38)	METAXLMERTKRETFGFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020124515-A1	QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF	东莞市东阳光农药研发有限公司	2020-06-25	—	—	WO	disclosed