Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 3/20 | 0.35 |
| ▸ | AXL | P30530 | 2/20 | 0.35 |
| ▸ | MERTK | Q12866 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149088 | 0.90 | DOT1L (0.37) | SRCTGFBR1DOT1LMETAXL | |
| SCHEMBL22148999 | 0.90 | TTR (0.39) | METAXLMERTKSMN1; SMN2KDR | |
| SCHEMBL22149104 | 0.89 | SRC (0.40) | SRCTGFBR1METAXLMERTK | |
| SCHEMBL22149059 | 0.89 | MET (0.38) | SRCTGFBR1METAXLMERTK | |
| SCHEMBL22149060 | 0.87 | SRC (0.37) | SRCTGFBR1METAXLMERTK | |
| SCHEMBL22149101 | 0.85 | KDR (0.43) | METAXLMERTKHTTKDR | |
| SCHEMBL22149080 | 0.84 | PDGFRA (0.41) | METAXLMERTKKDRIDO1 | |
| SCHEMBL22148994 | 0.83 | MET (0.51) | SRCMETAXLMERTKKDR | |
| SCHEMBL22149082 | 0.83 | MET (0.36) | SRCTGFBR1METAXLMERTK | |
| SCHEMBL22149145 | 0.79 | RXRA (0.34) | METAXLMERTKSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |