Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22148988 | 0.84 | PPIA (0.46) | PTPN2PTPN1PTPN6RXRARXRB | |
| SCHEMBL22149137 | 0.82 | PTPN1 (0.46) | MGLLPTPN2PTPN1PTPN6RXRA | |
| SCHEMBL22148986 | 0.82 | PTPN1 (0.48) | PTPN2PTPN1PTPN6RXRARXRB | |
| SCHEMBL25837396 | 0.81 | PTPN1 (0.49) | MGLLPTPN2PTPN1PTPN6RXRA | |
| SCHEMBL25837411 | 0.80 | PTPN1 (0.45) | PTPN2PTPN1PTPN6RXRARXRB | |
| SCHEMBL22145142 | 0.80 | ALDH1A1 (0.48) | MGLLPTPN1SMN1; SMN2PPIAKDR | |
| SCHEMBL22149016 | 0.79 | PTPN1 (0.43) | PTPN2PTPN1PTPN6RXRARXRB | |
| SCHEMBL25837414 | 0.78 | PTPN1 (0.44) | MGLLPTPN2PTPN1PTPN6RXRA | |
| SCHEMBL22163295 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1HPGDRAB9AKMT2A | |
| SCHEMBL22163084 | 0.73 | TLR7 (0.49) | MGLLPTPN2PTPN1PTPN6RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317129-A1 | Indolenaphthopyrans | TRANSITIONS OPTICAL, LTD. (IE) | 2021-10-14 | — | — | US | disclosed |
| WO-2020126030-A1 | INDOLENAPHTHOPYRANS AND PHOTOCHROMIC COMPOSITIONS COMPRISING THEM | TRANSITIONS OPTICAL, LTD. (IE) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126029-A1 | ARTICLES COMPRISING INDOLENAPHTHOPYRANS | TRANSITIONS OPTICAL, LTD. (IE) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317129-A1 | Indolenaphthopyrans | AHR, TDO2, TPH2 | MGLL 4400/4885PTPN2 848/4885PTPN1 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.