Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 5/20 | 0.34 |
| ▸ | AXL | P30530 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149145 | 0.85 | RXRA (0.34) | SLC22A12METAXLLMNAGAA | |
| SCHEMBL22149075 | 0.84 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL22148990 | 0.84 | IDO1 (0.35) | METAXLMGLLMAPTRET | |
| SCHEMBL22149104 | 0.80 | SRC (0.40) | METAXLSMN1; SMN2RETMERTK | |
| SCHEMBL22149077 | 0.79 | IRAK4 (0.49) | LMNASMN1; SMN2MAPTHSD17B10IRAK4 | |
| SCHEMBL22148994 | 0.79 | MET (0.51) | METAXLRETMERTKFGFR2 | |
| SCHEMBL22149101 | 0.79 | KDR (0.43) | METAXLMERTKHTTFGFR2 | |
| SCHEMBL22149082 | 0.78 | MET (0.36) | METAXLMERTKFGFR2 | |
| SCHEMBL22149148 | 0.78 | SRC (0.38) | METAXLSMN1; SMN2MERTKHTT | |
| SCHEMBL22149059 | 0.78 | MET (0.38) | METAXLMERTKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |