Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.37 |
| ▸ | TYMP | P19971 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21023599 | 0.83 | GNAO1 (0.38) | GNAI3GNAO1GNAI1 | |
| SCHEMBL21342942 | 0.81 | AKR1C3 (0.39) | AKR1C3TYMPMMP3MMP8GNAI3 | |
| SCHEMBL1501881 | 0.79 | AKR1C3 (0.43) | AKR1C3GNAI3GNAO1GNAI1 | |
| SCHEMBL14344736 | 0.79 | CPN1 (0.41) | AKR1C3TYMPBRD4MMP3MMP8 | |
| SCHEMBL22526178 | 0.79 | HSD17B10 (0.33) | — | |
| SCHEMBL22856502 | 0.79 | GNAO1 (0.45) | GNAI3GNAO1GNAI1 | |
| SCHEMBL13434207 | 0.78 | BRD4 (0.38) | AKR1C3BRD4 | |
| SCHEMBL22756299 | 0.78 | EPHX2 (0.35) | GNAI3GNAO1GNAI1 | |
| SCHEMBL13073774 | 0.77 | AKR1C3 (0.37) | AKR1C3GNAI3GNAO1GNAI1 | |
| SCHEMBL24258280 | 0.77 | NCF1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |