Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | IAPP | P10997 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FOS | P01100 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16120484 | 1.00 | MEN1 (0.41) | MEN1KMT2AALDH1A1NTRK1NPC1 | |
| SCHEMBL4712409 | 0.88 | MEN1 (0.44) | MEN1KMT2AALDH1A1NTRK1LMNA | |
| SCHEMBL4714245 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL10192488 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL16094770 | 0.80 | MEN1 (0.45) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16120485 | 0.80 | MEN1 (0.45) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL1521592 | 0.78 | LMNA (0.40) | MEN1KMT2AALDH1A1NTRK1NPC1 | |
| SCHEMBL16094560 | 0.75 | FBP1 (0.39) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL24885934 | 0.75 | RAB9A (0.50) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16370470 | 0.75 | MEN1 (0.49) | MEN1KMT2AALDH1A1NTRK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968331-B1 | PYRIMIDINE COMPOUNDS AS KINASE INHIBITORS | ICAHN SCHOOL MED MOUNT SINAI (US) | 2020-07-01 | — | — | EP | claimed |