SCHEMBL2215255

SCHEMBL2215255

NCCCCCn1ccc(=O)[nH]c1=O

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DUT P33316 13/20 0.54
NAAA Q02083 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.48
PDE3A Q14432 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL912535 0.98 DUT (0.55) DUTNAAAL3MBTL1PDE3A
SCHEMBL4957852 0.93 DUT (0.55) DUTNAAAL3MBTL1PDE3A
SCHEMBL2990980 0.85 L3MBTL1 (0.53) DUTL3MBTL1
SCHEMBL30903389 0.83 DUT (0.58) DUTNAAAL3MBTL1PDE3A
SCHEMBL25368590 0.83 NAAA (0.54) DUTNAAAL3MBTL1PDE3A
SCHEMBL17372138 0.83 DUT (0.55) DUTNAAA
SCHEMBL913034 0.83 NAAA (0.54) DUTNAAAL3MBTL1PDE3A
SCHEMBL7181572 0.83 DUT (0.54) DUTNAAAL3MBTL1PDE3A
SCHEMBL24205032 0.83 NAAA (0.54) DUTNAAAL3MBTL1PDE3A
SCHEMBL913371 0.83 NAAA (0.54) DUTNAAAL3MBTL1PDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120051575-A Detection of modified nucleobases in nucleic acid samples 豪夫迈·罗氏有限公司 2025-05-27 CN claimed
EP-2342616-A2 CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION Alnylam Pharmaceuticals Inc. (US) 2011-07-13 EP disclosed
WO-2010039548-A2 CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION ALNYLAM PHARMACEUTICALS, INC. (US) 2010-04-08 WO disclosed
US-7582748-B2 efficient synthetic route to an optionally protected 1-halo-2-deoxyribose; formation of an alkyl acetal, such as a methyl acetal, of a furanose, such as 2-deoxyribose, optionally protecting the remaining hydroxyl groups of the furanose, reacting the acetal with an acyl halide that forms the acid halide MICROBIOLOGICA QUIMICA E FARMACEUTICAL LTD. (BR) 2009-09-01 US disclosed
EP-1745573-A2 METHODS OF MANUFACTURE OF 2 -DEOXY-&bgr;-L-NUCLEOSIDES Microbiologica Quimica E Farmaceutica Ltd. (BR) 2007-01-24 EP disclosed
US-20040266996-A1 Methods of manufacture of 2'-deoxy-beta-L-nucleosides MICROBIOLOGICA QUIMICA E FARMACEUTICA LTD. (BR) 2004-12-30 US disclosed
WO-2004084453-A2 METHODS OF MANUFACTURE OF 2'-DEOXY-β-L-NUCLEOSIDES MICROBIOLOGICA QUIMICA E FARMACEUTICA LTD. (BR) 2004-09-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040266996-A1 Methods of manufacture of 2'-deoxy-beta-L-nucleosides DUT, DAO, DCTD DUT 1/4885NAAA 107/4885L3MBTL1 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.