SCHEMBL2990980

SCHEMBL2990980

NCCn1ccc(=O)[nH]c1=O

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.53
DUT P33316 11/20 0.51
CRBN Q96SW2 2/20 0.50
PKM P14618 1/20 0.49
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4957852 0.89 DUT (0.55) L3MBTL1DUTCRBNPKM
SCHEMBL4348697 0.87 L3MBTL1 (0.59) L3MBTL1DUTCRBNPKMALDH1A1
SCHEMBL912535 0.87 DUT (0.55) L3MBTL1DUTCRBN
SCHEMBL2215255 0.85 DUT (0.54) L3MBTL1DUT
SCHEMBL6102943 0.85 CRBN (0.56) L3MBTL1DUTCRBNPKMALDH1A1
SCHEMBL3235869 0.84 L3MBTL1 (0.53) L3MBTL1DUTCRBNPKMALDH1A1
SCHEMBL14861415 0.82 L3MBTL1 (0.54) L3MBTL1DUTCRBNPKMALDH1A1
SCHEMBL31592762 0.81 L3MBTL1 (0.58) L3MBTL1DUTCRBNPKMALDH1A1
SCHEMBL2983407 0.80 ALDH1A1 (0.57) L3MBTL1DUTCRBNPKMALDH1A1
SCHEMBL16632410 0.80 L3MBTL1 (0.53) L3MBTL1DUTCRBNPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4605545-A1 DETECTION OF MODIFIED NUCLEOBASES IN NUCLEIC ACID SAMPLES F. Hoffmann-La Roche AG (CH) 2025-08-27 EP claimed
CN-120051575-A Detection of modified nucleobases in nucleic acid samples 豪夫迈·罗氏有限公司 2025-05-27 CN claimed
WO-2024083982-A1 DETECTION OF MODIFIED NUCLEOBASES IN NUCLEIC ACID SAMPLES F. HOFFMANN-LA ROCHE AG (CH) 2024-04-25 WO claimed
EP-4605545-A1 DETECTION OF MODIFIED NUCLEOBASES IN NUCLEIC ACID SAMPLES F. Hoffmann-La Roche AG (CH) 2025-08-27 EP disclosed
CN-120051575-A Detection of modified nucleobases in nucleic acid samples 豪夫迈·罗氏有限公司 2025-05-27 CN disclosed
US-12018260-B2 Tunable Reversir™ compounds ALNYLAM PHARMACEUTICALS, INC. (US) 2024-06-25 US disclosed
CN-117957328-A Polynucleotide and use thereof 斯特兰德生物科技公司 2024-04-30 CN disclosed
WO-2024083982-A1 DETECTION OF MODIFIED NUCLEOBASES IN NUCLEIC ACID SAMPLES F. HOFFMANN-LA ROCHE AG (CH) 2024-04-25 WO disclosed
CN-111378162-A Energy absorption method based on dynamic polymer 翁秋梅 2020-07-07 CN disclosed
US-7777024-B2 Process for preparing a pentopyranosyl nucleic acid conjugate AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. (DE) 2010-08-17 US disclosed
US-20090221793-A1 PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE SANOFI-AVENTIS S.A. (FR) 2009-09-03 US disclosed
EP-1034180-A2 LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME Nanogen Recognomics GmbH (DE) 2000-09-13 EP disclosed
EP-1019423-A2 METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE Nanogen Recognomics GmbH (DE) 2000-07-19 EP disclosed
EP-1017704-A2 USE OF A PENTOPYRANOSYL NUCLEOSIDE CONTAINING CONJUGATE FOR PRODUCING AN ARRAY Nanogen Recognomics GmbH (DE) 2000-07-12 EP disclosed
EP-1017703-A2 PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME Nanogen Recognomics GmbH (DE) 2000-07-12 EP disclosed
WO-1999052923-A2 METHOD FOR THE PRODUCTION OF PENTOPYRANOSYL NUCLEOSIDES AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-10-21 WO disclosed
WO-1999015540-A2 METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1999-04-01 WO disclosed
WO-1999015542-A2 LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-01 WO disclosed
WO-1999015539-A2 PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-01 WO disclosed
WO-1999015541-A2 USE OF A PENTOPYRANOSYL NUCLEOSIDE FOR PRODUCING AN ELECTRONIC COMPONENT, AND CONJUGATES OF SAID PENTOPYRANOSYL NUCLEOSIDE AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221793-A1 PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE RNGTT, NT5C3B, FUT6 L3MBTL1 1933/4885DUT 11/4885CRBN 1660/4885
US-12018260-B2 Tunable Reversir™ compounds SNRPE, PLK1, LDLR L3MBTL1 2390/4885DUT 228/4885CRBN 1159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.