SCHEMBL22156458

SCHEMBL22156458

N#Cc1c(-n2c3ccccc3c3cc(-c4ccnc(-c5ccccc5)c4)ccc32)cc(-c2cc(F)cc(F)c2)cc1-n1c2ccccc2c2cc(-c3ccnc(-c4ccccc4)c3)ccc21

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 5/20 0.36
ADORA2A P29274 2/20 0.35
ADORA1 P30542 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
TGFBR1 P36897 2/20 0.33
MAPK14 Q16539 1/20 0.33
PGR P06401 1/20 0.32
NTRK1 P04629 1/20 0.32
NTRK3 Q16288 1/20 0.32
NTRK2 Q16620 1/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAP4K4 O95819 1/20 0.31
GRM5 P41594 1/20 0.31
ADORA2B P29275 1/20 0.31
PIM1 P11309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22156811 0.97 ADORA2A (0.37) SQORADORA2AADORA1KDM4EHPGD
SCHEMBL22156455 0.94 SQOR (0.36) SQORADORA2AADORA1KDM4EHPGD
SCHEMBL22156813 0.91 ADORA2A (0.37) SQORADORA2AADORA1KDM4EHPGD
SCHEMBL22156882 0.89 SQOR (0.33) SQORADORA2AADORA1KDM4EHPGD
SCHEMBL22155914 0.88 PGR (0.37) SQORADORA2AADORA1KDM4EHPGD
SCHEMBL22155880 0.88 TGFBR1 (0.34) SQORADORA2AADORA1KDM4EHPGD
SCHEMBL21547043 0.88 GABRG2 (0.41) ADORA2AADORA1TGFBR1MAPK1MAP4K4
SCHEMBL22156765 0.88 NPSR1 (0.37) SQORADORA2AADORA1KDM4EHPGD
SCHEMBL22157172 0.87 SQOR (0.35) SQORADORA2AADORA1KDM4EHPGD
SCHEMBL22156412 0.86 GRM5 (0.36) TGFBR1MAPK14PGRMAP4K4GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3635070-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-04-28 EP disclosed
US-20200203628-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200203628-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, OR51E2 SQOR 302/4885ADORA2A 4520/4885ADORA1 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.