SCHEMBL221583

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL220479	0.80	EPHX1 (0.55)	LMNAALDH1A1KMT2AKDM4EMEN1
	SCHEMBL5526125	0.78	NOTUM (0.50)	ALDH1A1KMT2AKDM4EGAAMAPT
	SCHEMBL17640894	0.77	NOTUM (0.48)	ADORA2AADORA3ADORA2BADORA1LMNA
	SCHEMBL219165	0.73	ALDH1A1 (0.48)	ALDH1A1KMT2AKDM4EMEN1GAA
	SCHEMBL221069	0.72	ADORA2A (0.42)	ADORA2AADORA3ADORA2BADORA1LMNA
	SCHEMBL220480	0.70	KAT6A (0.39)	LMNATP53FGFR1
	SCHEMBL6209994	0.69	MAPT (0.43)	LMNAALDH1A1KMT2AKDM4EMEN1
	SCHEMBL221584	0.68	LMNA (0.36)	ADORA2AADORA3ADORA2BADORA1LMNA
	SCHEMBL14861347	0.67	FGFR1 (0.47)	ADORA2AADORA1LMNAALDH1A1KMT2A
	SCHEMBL29080878	0.66	NOTUM (0.48)	ADORA2AADORA3ADORA2BADORA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.