SCHEMBL22159668

SCHEMBL22159668

CC1(C)OB(c2c(Oc3ccccc3)cccc2Oc2ccccc2Cl)OC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.43
EZH2 Q15910 1/20 0.38
ALDH1A1 P00352 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
LPL P06858 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
POLB P06746 2/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
CXCL8 P10145 1/20 0.35
XIAP P98170 1/20 0.35
HPGD P15428 1/20 0.34
GAA P10253 2/20 0.34
LPAR1 Q92633 1/20 0.34
LPAR5 Q9H1C0 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
MMP14 P50281 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16139819 0.90 LPL (0.43) DPP4ALDH1A1LPLLIPGSLC6A2
SCHEMBL22159677 0.87 HTR2A (0.41) DPP4ALDH1A1NPSR1LPLLIPG
SCHEMBL23406401 0.85 SLC6A4 (0.46) DPP4ALDH1A1NPSR1LPLLIPG
SCHEMBL17423585 0.81 LPL (0.50) EZH2LPLLIPGXIAPMMP14
SCHEMBL23406341 0.80 SLC6A4 (0.46) SLC6A2SLC6A4SLC6A3LMNAL3MBTL1
SCHEMBL4356244 0.76 LPL (0.47) LPLLIPG
Ethane SCHEMBL27569819 0.75 DPP4 (0.58) DPP4ALDH1A1NPSR1SLC6A2SLC6A4
SCHEMBL3790160 0.74 DPP4 (0.62) DPP4ALDH1A1NPSR1SLC6A2SLC6A4
SCHEMBL30526881 0.73 EGFR (0.37) ALDH1A1LPLLIPGPOLBLMNA
SCHEMBL31636019 0.73 LPL (0.42) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-07 US disclosed
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-03-07 US disclosed
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-15 US disclosed
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-15 US disclosed
US-20210167288-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-06-03 US disclosed
US-20210167288-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-06-03 US disclosed
US-20200207787-A1 POLYCYCLIC AROMATIC COMPOUND, MATERIAL FOR AN ORGANIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY APPARATUS AND LIGHTING APPARATUS KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-07-02 US disclosed
US-20200207787-A1 POLYCYCLIC AROMATIC COMPOUND, MATERIAL FOR AN ORGANIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY APPARATUS AND LIGHTING APPARATUS KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus TYR, AOC2, AOC1 DPP4 3355/4885EZH2 202/4885ALDH1A1 791/4885
US-20210167288-A1 POLYCYCLIC AROMATIC COMPOUND ARNT, TYR, AHR DPP4 2410/4885EZH2 292/4885ALDH1A1 1253/4885
US-11600790-B2 Polycyclic aromatic compound for organic electroluminescent device AOC2, TYR, BMI1 DPP4 2984/4885EZH2 128/4885ALDH1A1 1181/4885
US-20200207787-A1 POLYCYCLIC AROMATIC COMPOUND, MATERIAL FOR AN ORGANIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY APPARATUS AND LIGHTING APPARATUS TYR, AOC2, AOC1 DPP4 3355/4885EZH2 202/4885ALDH1A1 791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.