Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811649 | 0.79 | CA12 (0.56) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL29800427 | 0.79 | CA12 (0.56) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL28779574 | 0.78 | MKNK1 (0.46) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL2218769 | 0.77 | CYP1A2 (0.41) | SMN1; SMN2TP53MAPTCDKN1ANPC1 | |
| SCHEMBL6178023 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL5964500 | 0.75 | OXTR (0.48) | SMN1; SMN2TP53MAPTNPC1RAB9A | |
| SCHEMBL4651619 | 0.75 | CYP1A2 (0.47) | SMN1; SMN2TP53MAPTNPC1RAB9A | |
| SCHEMBL1222552 | 0.74 | NPC1 (0.62) | SMN1; SMN2TP53MAPTNPC1RAB9A | |
| SCHEMBL12380464 | 0.74 | HCAR3 (0.60) | SMN1; SMN2MAPTJAK3JAK2JAK1 | |
| SCHEMBL18104381 | 0.74 | CA12 (0.50) | SMN1; SMN2MAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638964-B1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-07-27 | — | — | EP | disclosed |