SCHEMBL22163727

SCHEMBL22163727

C=CN(C(=C)/C=C\C)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ TRPM8 Q7Z2W7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23436491 0.84 TRPM8 (0.33) MEN1KMT2ATRPM8
SCHEMBL23652017 0.79 MEN1 (0.34) MEN1KMT2ATRPM8
SCHEMBL20172629 0.77 FAAH (0.42) MEN1KMT2A
SCHEMBL16906012 0.76 MEN1 (0.31) MEN1KMT2A
SCHEMBL22694031 0.76 — —
SCHEMBL21795024 0.73 LMNA (0.31) MEN1KMT2A
SCHEMBL20427770 0.73 ALDH1A1 (0.52) MEN1KMT2ATRPM8
SCHEMBL18935538 0.72 ALDH1A1 (0.37) MEN1KMT2A
SCHEMBL24863101 0.71 — —
SCHEMBL273919 0.71 KMT2A (0.46) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3670132-A1 TIRE PRODUCTION METHOD, AND TIRE Bridgestone Corporation (JP) 2020-06-24 — — EP disclosed
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