Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 13/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 10/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 10/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KIFC1 | Q9BW19 | 5/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532331 | 0.94 | L3MBTL1 (0.34) | PLGPRSS1PRSS2PRSS3PLAU | |
| SCHEMBL22167260 | 0.92 | L3MBTL1 (0.32) | PLGPRSS1PRSS2PRSS3PLAU | |
| SCHEMBL22167457 | 0.92 | PLG (0.31) | PLGPRSS1PRSS2PRSS3PLAU | |
| SCHEMBL22167479 | 0.91 | KIFC1 (0.35) | KIFC1 | |
| SCHEMBL17539189 | 0.91 | KIFC1 (0.35) | KIFC1 | |
| SCHEMBL19695865 | 0.91 | HPGDS (0.33) | — | |
| SCHEMBL17532332 | 0.90 | PSMB2 (0.33) | KIFC1 | |
| SCHEMBL17459567 | 0.90 | MME (0.32) | KIFC1 | |
| SCHEMBL19695848 | 0.90 | MME (0.32) | KIFC1 | |
| SCHEMBL17532357 | 0.89 | L3MBTL1 (0.33) | PLGPRSS1PRSS2PRSS3PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |