Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.37 |
| ▸ | MME | P08473 | 4/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | GIPR | P48546 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20026746 | 0.93 | HPGDS (0.38) | MMEGCGRGIPRHPGDSLNPEP | |
| SCHEMBL17532315 | 0.92 | MME (0.36) | MMEGCGRGIPRHPGDSLNPEP | |
| SCHEMBL17532329 | 0.90 | MME (0.36) | MMEHPGDSLNPEP | |
| SCHEMBL22167463 | 0.90 | GCGR (0.32) | GCGRGIPRHPGDSLNPEP | |
| SCHEMBL20026814 | 0.88 | PYGL (0.34) | GCGRGIPRHPGDSITGB1ITGA4 | |
| SCHEMBL22167488 | 0.86 | ITGA4 (0.35) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL17532369 | 0.86 | ITGA4 (0.35) | KIFC1MMEACEACE2ITGB1 | |
| SCHEMBL22167460 | 0.86 | PRCP (0.35) | ITGB3ITGA2B | |
| SCHEMBL15019919 | 0.85 | MME (0.42) | KIFC1MMEACEACE2HPGDS | |
| SCHEMBL15019922 | 0.85 | MME (0.42) | KIFC1MMEACEACE2HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |