SCHEMBL22167684

SCHEMBL22167684

CCC(=O)N1CCOC(C)(C(C)C)CC1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.39
ALDH1A1 P00352 4/20 0.39
BLM P54132 1/20 0.36
TSHR P16473 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 4/20 0.34
FKBP1A P62942 4/20 0.34
MEN1 O00255 3/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
RAB9A P51151 1/20 0.33
CASP7 P55210 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
EPHX2 P34913 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
OPRD1 P41143 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22167668 0.78 CYP2C9 (0.48) ALDH1A1TSHRKMT2AMEN1MAPK1
SCHEMBL12259441 0.74 OPRM1 (0.42) OPRM1ALDH1A1BLMTSHRL3MBTL1
SCHEMBL21480181 0.73 OPRM1 (0.41) OPRM1ALDH1A1BLMTSHRL3MBTL1
SCHEMBL13360773 0.73 KMT2A (0.58) ALDH1A1TSHRL3MBTL1KMT2AMEN1
SCHEMBL13360768 0.72 ALDH1A1 (0.52) OPRM1ALDH1A1BLMTSHRL3MBTL1
SCHEMBL17616420 0.71 SMN1; SMN2 (0.44) ALDH1A1TSHRKMT2ANPC1MAPK1
SCHEMBL15247314 0.71 OPRM1 (0.41) OPRM1ALDH1A1BLMTSHRL3MBTL1
SCHEMBL20671838 0.71 ALDH1A1 (0.48) OPRM1ALDH1A1BLMTSHRSMN1; SMN2
SCHEMBL12526186 0.71 OPRM1 (0.42) OPRM1ALDH1A1BLMTSHRKMT2A
SCHEMBL17172989 0.70 ALDH1A1 (0.47) OPRM1ALDH1A1BLML3MBTL1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3889154-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Wuhan LL Science And Technology Development Co., Ltd. (CN) 2021-10-06 EP disclosed
WO-2020135771-A1 HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2020-07-02 WO disclosed