SCHEMBL22168565

SCHEMBL22168565

CC(C)Cc1cc(-c2ccc(F)cc2)ncc1[Si](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 2/20 0.36
IDO1 P14902 1/20 0.36
CXCR1 P25024 1/20 0.35
MAPK14 Q16539 2/20 0.34
RET P07949 2/20 0.34
NPC1 O15118 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
AURKA O14965 1/20 0.34
ABL1 P00519 1/20 0.34
NTRK1 P04629 1/20 0.34
LCK P06239 1/20 0.34
CSF1R P07333 1/20 0.34
MET P08581 1/20 0.34
PDGFRB P09619 1/20 0.34
PIM1 P11309 1/20 0.34
PDGFRA P16234 1/20 0.34
FLT3 P36888 1/20 0.34
MAPK8 P45983 1/20 0.34
CDK8 P49336 1/20 0.34
MAP2K1 Q02750 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23416511 0.87 NPC1 (0.35) MAPK14RETNPC1AURKAABL1
SCHEMBL17637115 0.85 ADORA1 (0.38) TDO2IDO1NPC1
SCHEMBL17811395 0.80 SGK1 (0.36) ALOX5APFEN1
SCHEMBL29492597 0.79 CYP11B1 (0.40) PIM1MAPTKDM4EALDH1A1HPGD
SCHEMBL17637117 0.78 KMO (0.37) TDO2IDO1
SCHEMBL27239420 0.78 TDO2 (0.39) TDO2IDO1CXCR1MAPK14RET
SCHEMBL17637122 0.77
SCHEMBL18540389 0.77 TP53 (0.43) IDO1NPC1MAPTDPP4KDM4E
SCHEMBL25665358 0.76 HDAC1 (0.38) ALOX5APFEN1
SCHEMBL18540388 0.76 WNK1 (0.36) CXCR1ALOX5APFEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11672167-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-06 US disclosed
US-11672167-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-06 US disclosed
US-20200212323-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212323-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYC1, CYBA TDO2 356/4885IDO1 394/4885CXCR1 702/4885
US-11672167-B2 Organometallic compound and organic light-emitting device including the same CRY1, CYC1, CYBA TDO2 356/4885IDO1 394/4885CXCR1 702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.