Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | FPR2 | P25090 | 4/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.56 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434172 | 0.83 | CASR (1.00) | CASRRAB9ASMN1; SMN2NPC1FPR2 | |
| SCHEMBL22170204 | 0.83 | CASR (0.75) | CASRRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL20708118 | 0.83 | SMN1; SMN2 (0.68) | CASRRAB9ASMN1; SMN2NPC1FPR2 | |
| SCHEMBL8577837 | 0.83 | SMN1; SMN2 (0.68) | CASRRAB9ASMN1; SMN2NPC1FPR2 | |
| SCHEMBL1912325 | 0.81 | CNR1 (0.67) | CASRRAB9ASMN1; SMN2NPC1FPR2 | |
| SCHEMBL3146895 | 0.81 | FPR2 (0.66) | CASRRAB9ASMN1; SMN2NPC1FPR2 | |
| SCHEMBL10223997 | 0.81 | SMN1; SMN2 (0.73) | CASRRAB9ASMN1; SMN2NPC1EPHX2 | |
| SCHEMBL10598972 | 0.80 | SMN1; SMN2 (0.64) | CASRRAB9ASMN1; SMN2NPC1FPR2 | |
| SCHEMBL16562079 | 0.80 | FPR2 (0.86) | RAB9ASMN1; SMN2NPC1FPR2CNR1 | |
| SCHEMBL1499493 | 0.80 | NPC1 (0.62) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840543-B2 | Compounds and uses | THE UNIVERSITY OF QUEENSLAND (AU) | 2023-12-12 | — | — | US | disclosed |
| US-20200207780-A1 | NOVEL COMPOUNDS AND USES | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840543-B2 | Compounds and uses | NLRP3, NOD1, IAPP | CASR 301/4885RAB9A 2420/4885SMN1; SMN2 4240/4885 |
| US-20200207780-A1 | NOVEL COMPOUNDS AND USES | NLRP3, NOD1, GPR119 | CASR 265/4885RAB9A 2119/4885SMN1; SMN2 4277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.